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Medical News Today (Free subscription) | yesterday
Biogen Idec (NASDAQ: BIIB) announced today that its Phase II trial of baminercept (BG9924, LTßR-Ig) in rheumatoid arthritis (RA) patients who have had an inadequate response to conventional therapy with a disease-modifying antirheumatic drug (DMARD) did not meet its primary endpoint. The primary endpoint was defined as the proportion of baminercept-treated patients who achieved an ACR50 response, a...
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Physorg (Free subscription) | yesterday
Essential for life in higher animals, vitamin D, once linked to only bone diseases such as rickets and osteoporosis, is now recognized as a major player in contributing to overall human health, emphasizes UC Riverside's Anthony Norman, an international expert on vitamin D.
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Medical News Today (Free subscription) | 10/09/2008
Lumbar spine (lower back) surgery is a common treatment for a herniated or "slipped" disk, and patients need to know whether it is better to sit still or get moving during their recovery period. An updated review from the Netherlands suggests that exercise programs starting four to six weeks after the operation could lead to more rapid pain relief and a quicker recovery from disability without increasing...
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Science Daily (Free subscription) | 10/09/2008
Vitamin D, once linked to only bone diseases, is now recognized as a major player in contributing to overall human health, emphasizes UC Riverside's Anthony Norman, an international expert on vitamin D. He lists 36 organ tissues in the body whose cells respond biologically to vitamin D. The list includes bone marrow, breast, colon, intestine, kidney, lung, prostate, retina, skin, stomach and the uterus....
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Medical News Today (Free subscription) | 10/08/2008
Ferring Pharmaceuticals Inc. recently presented results from the FLEXX Trial of Osteoarthritis of the Knee, showing that EUFLEXXA(R) (1% sodium hyaluronate), a highly pure non-avian high molecular weight form of intra-articular hyaluronic acid (IA-HA), is superior to intra-articular saline (IA-saline) for the relief of pain in knee osteoarthritis (OA) at 26 weeks.
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Seeking Alpha (Free subscription) | 10/06/2008
Mike Havrilla submits: Some likely near-term movers on the FDA's decision date calendar for 70 different items ( click to enlarge, left ) include Cypress Bioscience (CYPB) + partner Forest Labs (FRX) with a pending decision on milnacipran in the treatment of fibromyalgia slated for the end of October in addition to results from a Phase 3 trial for the drug some time before year end. Complete Story...
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Fighting Fatigue (Free subscription) | 10/05/2008
Topical gabapentin has been found to be a well tolerated, effective treatment for relieving the pain of localized and generalized vulvodynia, according to a report in the September issue of Obstetrics & Gynecology. Topical Gabapentin Found Useful For Vulvodynia I found some astonishing statistics a while back on the various aspects of chronic illness. One statistic that really [...]
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Medical News Today (Free subscription) | 10/04/2008
If a hip prosthesis implanted to replace a worn-out joint itself fails, then what are the reasons? Until now this problem has been little understood: partly due to incomplete records, partly due to insufficient knowledge of the forces acting on the hip replacement. Computation models developed by the University of Twente and UMC St. Radboud can make an important contribution to our understanding in...
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Red Orbit (Free subscription) | 09/29/2008
News in brief SCIENCE A protein which may ease the pain for millions of people who suffer from bone disease has been discovered.
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Medical News Today (Free subscription) | 09/17/2008
Drug company Merck said its investigational drug odanacatib (formerly MK-0822) for the treatment of osteoporosis in postmenopausal women showed promise after 24 months in a Phase IIB trial where compared to placebo it significantly increased bone mineral density (BMD). The findings were announced on Tuesday 16th September at the 30th Annual Meeting of the American Society for Bone and Mineral Research...
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Red Orbit (Free subscription) | 09/14/2008
By Kraenzlin, Marius E Kraenzlin, Claude A; Meier, Christian; Giunta, Cecilia; Steinmann, Beat BACKGROUND: The pyridinium cross-links pyridinoline (PYD) and deoxypyridinoline (DPD) are established markers of bone resorption.
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Fighting Fatigue (Free subscription) | 09/05/2008
According to a study published August 22 in the Journal of Biological Chemistry, researchers have discovered how rheumatoid arthritis destroys bone. Thanks to these findings, new drug ideas are already in the works that will help to reverse the bone loss due to RA. Among the immune chemicals known to play a central in autoimmune disease [...]
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Medical News Today (Free subscription) | 09/02/2008
MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) announced today the publication of a first data package for its most advanced proprietary drug development program MOR103, a fully human HuCAL antibody directed against GM-CSF, in the journal "Molecular Immunology". The data presented shows that MOR103 is able to block disease-relevant processes such as GM-CSF dependent proliferation and signal...
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Fighting Fatigue (Free subscription) | 09/02/2008
Sex & IC Disease (Part 5): What To Do After Sex What a woman does after having sexual intercourse can affect how bad her IC Disease symptoms flare. As I have mentioned in my other posts on sex & IC Disease (please refer to Part 1, Part 2, Part 3 & Part 4 if you haven’t [...]
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Medical News Today (Free subscription) | 08/13/2008
Patients who use proton pump inhibitors for 7 or more years to treat reflux, peptic ulcers and other conditions are at greater risk of osteoporosis-related fractures, according to this large observational study, http://www.cmaj.ca/press/pg319.pdf, of 15,792 patients published in CMAJ.
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euro puppy | 01/22/2008
This article looks at how the revolutionary BARF diet (Biologically Appropriate Raw Food Diet) for large dogs helps to prevent bone diseases. Very informative and well written!
