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Howard Hughes


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Immune Response To Human Embryonic Stem Cells In Mice Suggests Human Therapy May Face Challenge

Human embryonic stem cells trigger an immune response in mice, researchers from the Stanford University School of Medicine report. The finding suggests that the effectiveness of human therapies derived from the cells could be limited unless ways are found to dampen the rejection response.

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Clays May Have Aided Formation of Primordial Cells

October 24, 2003 Clays May Have Aided Formation of Primordial Cells Howard Hughes Medical Institute (HHMI) researchers have discovered that clays may have been the catalysts that spurred the spontaneous assembly of fatty acids into the small sacs that ultimately evolved into the first living cells. HHMI investigator Jack W. Szostak and colleagues Martin M. Hanczyc and Shelly M. Fujikawa at Massachusetts...

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Scientists Make Precancerous Cells Self-Destruct By Amplifying Cell Death Signals

When a cell begins to multiply in a dangerously abnormal way, a series of death signals trigger it to self-destruct before it turns cancerous. Now, in research Genes & Development, Rockefeller University scientists have figured out a way in mice to amplify the signals that tell these precancerous cells to die. The trick: Inactivating a protein that normally helps cells to avoid self-destruction.

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Spotted at Nordstrom Rack

Various Kerastase products including Bain Satin 2 and Chroma Reflect for $31.97 each. Not as thrifty as hunting these down on eBay, but you get the instant gratification of immediately running home to pamper your hair. Spotted at Nordstrom Rack at Howard Hughes Center.

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Gerhard Forde on being like Howard Hughes

‘We are like Howard Hughes, that pathetic modern parallel to the Rich Fool. We are so afraid of death and so caught up in defending ourselves against it, hiding from it, and denying it that in the end it kills us!’ - Gerhard O. Forde, Justification by Faith - A Matter of Death and Life [...]

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Robert A. Maheu: Aide to Howard Hughes

Robert A. Maheu knew what power was. It was when you called the White House, and asked to see Lyndon Johnson. In fact, the President was trying to snatch a few days off at his Texas ranch, but still had a helicopter sent to ferry his unexpected guest from the nearest airport. He would give another example. "If you can pick up the telephone the night before the Academy Awards and say, 'By the way,...

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'Dirty' jobs man who was Howard Hughes' adviser

Robert Maheu who died in Las Vegas, aged 90, was the 'public face' of the reclusive billionaire but never met his boss face-to-face

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By amplifying cell death signals, scientists make precancerous cells self-destruct

On the cellular level, death signals can actually be life saving -- by killing off abnormally dividing cells before they turn cancerous. Now, Rockefeller University researchers have found a way to amplify these signals by turning a life affirming protein into a killer. The findings not only mark a breakthrough in the field but also open the door to a new line of drugs for cancer therapeutics.

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Cocaine-induced changes linked to persistent addictive behaviours

Washington, Aug 14 : In two separate studies, scientists have identified specific cocaine-induced changes in dopamine (DA) neurons that play a vital role in persistent addictive behaviours linked with drugs.

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Can Exercise Come in a Pill?

A new drug works at the genetic level to change metabolism. But how effective is it? And is it safe?

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MicroRNA Activation Mystery Is Solved

U.S. scientists say they've discovered how microRNA molecules are activated -- an event that is critical for the creation of embryonic stem cells....

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The hangar opens and Richard Branson gives thumbs up

So here we were at 6.20am a couple of Mondays ago at Los Angeles International Airport. Despite the hour, a disc jockey played pulsing club music, a soundtrack that soon continued on board a Virgin America Airbus with “My Other Ride is a Spaceship” emblazoned behind its nose. A 20-minute flight later, the jet landed in Mojave, California, where Sir Richard Branson awaited.

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Childhood Brain Tumor Traced To Normal Stem Cells Gone Bad

An aggressive childhood brain tumor known as medulloblastoma originates in normal brain “stem” cells that turn malignant when acted on by a known mutant, cancer-causing oncogene, say researchers from Dana-Farber Cancer Institute and the University of California, San Francisco (UCSF). Reporting in the Aug. 12 issue of Cancer Cell, the scientists say they have uncovered new [...]

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New evidence of battle between humans and ancient virus

For millennia, humans and viruses have been locked in an evolutionary back-and-forth — one changes to outsmart the other, prompting the second to change and outsmart the first. With retroviruses, which work by inserting themselves into their host’s DNA, the evidence remains in our genes. Last year, researchers at Rockefeller University and the Aaron Diamond [...]

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Scientists Replicate Diseases in the Lab with New Stem Cell Lines

A set of new stem cell lines will make it possible for researchers to explore ten different genetic disorders-including muscular dystrophy, juvenile diabetes, and Parkinson's disease-in a variety of cell and tissue types as they develop in laboratory cultures.